What is the difference between unisom and benadryl

These are getting a lot of attention right now—like hydrocodone or oxycodone—because they are very addictive. They are commonly used to treat allergies and are generally safe. However, one of these drugs, Benadryl diphenhydramine , is commonly used in over-the-counter sleep agents.

Taking an over-the-counter sleep aid with diphenhydramine once in a while is generally not going to cause problems, other than a possible hangover the next day. Older people, however, can get confused when taking diphenhydramine because it also blocks a brain chemical called acetylcholine, which plays a big role in attention and short-term memory.

Taking diphenhydramine over a long period of time can actually predispose people to dementia. Was this article helpful? We'll never share your email with anyone else. Submit Close. Derue44 gmail. Related Questions. Am I taking too many supplements? Here are the supplements I take, and why I take them What are the potential side effects of taking Unisom?

Can I take Unisom for an allergy? Is Unisom safe when used as directed and effective? All Unisom formulas are safe when used as directed. What sizes are available? Should I consult my doctor first? Will Unisom interact with my medications? Can I take Unisom every night? Can I take Unisom if I wake up in the middle of the night? When should I take Unisom?

How do Unisom products work? How fast will Unisom products make me fall asleep? Why does Unisom make my mouth dry? You are about to leave Unisom. Do you want to continue? By Mayo Clinic Staff. Thank you for Subscribing Our Housecall e-newsletter will keep you up-to-date on the latest health information.

Please try again. Something went wrong on our side, please try again. Show references Bonnet MH, et al. Treatment of insomnia in adults. Accessed Jan. Schroeck JL, et al. Review of safety and efficacy of sleep medicines in older adults. Clinical Therapeutics. Culpepper L, et al. Over-the-counter agents for the treatment of occasional disturbed sleep or transient insomnia: A systematic review of efficacy and safety.

Kryger MH, et al. Pharmacologic treatment of insomnia: Other medications. In: Principles and Practice of Sleep Medicine. Louis, Mo. Petrov ME, et al. Over-the-counter and prescription sleep medication and incident stroke: The Reasons for Geographic and Racial Differences in Stroke study.

Journal of Stroke and Cardiovascular Disease.